Rank			Name		World Wide Sales (mm)			CAGR
2007	2006	Brand		Generic	2005	2006	2007	1 yr	3 yr		Company(s)
1	1		Lipitor	Atorvastatin	$13,378	$14,385	$12,700	-12%	-2%		Pfizer, Astellas Pharma
2	3		Plavix	Clopidogrel	$6,360	$6,057	$7,977	32%	8%		BMS, Sanofi-Aventis
3	2		Advair	Fluticasone + Salmeterol	$5,394	$6,129	$7,004	14%	9%		GSK
4	7		Enbrel	Etanercept	$3,503	$4,379	$5,375	23%	15%		Amgen, Wyeth
5	4		Nexium	Esomeprazole	$4,560	$5,182	$5,216	1%	5%		AstraZeneca
6	9		Diovan	Valsartan	$3,590	$4,223	$5,012	19%	12%		Novartis
7	6		Remicade	Infliximab	$3,410	$4,428	$4,975	12%	13%		J&J, Schering-Plough, Tanabe
8	8		Zyprexa	Olanzapine	$4,189	$4,364	$4,760	9%	4%		Eli Lilly
9	10		Risperdal	Risperidone	$3,430	$4,183	$4,696	12%	11%		J&J
10	12		Rituxan	Rituximab	$3,243	$3,861	$4,600	19%	12%		Roche, Genentech, Biogen, Chugai
11	15		Singulair	Montelukast	$2,863	$3,579	$4,300	20%	15%		Merck & Co.
12	21		Herceptin	Trastuzumab	$533	$3,134	$4,050	29%	97%		Roche, Genentech, Chugai
13	16		Seroquel	Quetiapine	$2,741	$3,560	$4,027	13%	14%		AstraZeneca, Astellas Pharma
14	22		Lovenox	Enoxaparin	$2,631	$3,210	$4,000	25%	15%		Sanofi-Aventis
15	13		Effexor	Venlafaxine	$3,424	$3,722	$3,794	2%	3%		Wyeth
16	11		Aranesp	Darbepoetin alfa	$3,050	$4,121	$3,614	-12%	6%		Amgen
17	5		Norvasc	Amlodipine	$4,720	$4,866	$3,510	-28%	-9%		Pfizer
18	36		Avastin	Bevacizumab	$520	$2,364	$3,425	45%	87%		Roche, Genentech
19	19		Cozaar	Losartan	$3,036	$3,163	$3,400	7%	4%		Merck & Co.
20	54		Atacand	Candesartan	$2,456	$2,889	$3,222	12%	9%		Takeda , AstraZeneca
21	27		AcipHex	Rabeprazole	$2,838	$2,729	$3,158	16%	4%		Eisai, J&J
22	41		Lantus	Insulin analog	$1,319	$2,093	$3,110	49%	33%		Sanofi-Aventis
23	43		Humira	Adalimumab	$1,104	$2,044	$3,064	50%	41%		Abbott
24	20		Fosamax	Alendronate	$3,197	$3,134	$3,050	-3%	-2%		Merck & Co.
25	30		Gleevec	Imatinib	$2,094	$2,554	$3,050	19%	13%		Novartis
26	29		Lexapro	Escitalopram	$2,265	$2,696	$3,045	13%	10%		Forest , H. Lundbeck
27	28		Neulasta	Filgrastim	$2,222	$2,710	$3,000	11%	11%		Amgen
28	24		Actos	Pioglitazone	$2,160	$2,880	$2,900	1%	10%		Takeda , Eli Lilly
29	18		Procrit	Erythropoietin	$3,307	$3,180	$2,885	-9%	-4%		J&J
30	37		Taxotere	Docetaxel	$2,003	$2,201	$2,870	30%	13%		Sanofi-Aventis
31	17		Prevacid	Lansoprazole	$3,322	$3,425	$2,868	-16%	-5%		TAP , Takeda
32	35		Avapro	Irbesartan	$2,064	$2,372	$2,854	20%	11%		Sanofi-Aventis, BMS
33	47		Vytorin	Ezetimibe+Simvastatin	$196	$1,955	$2,800	43%	143%		Merck & Co., Schering-Plough
34	42		Crestor	Rosuvastatin	$799	$2,049	$2,769	35%	51%		AstraZeneca, Shionogi
35	33		Epogen	Erythropoietin	$2,461	$2,511	$2,489	-1%	0%		Amgen
36	55		Spiriva	Tiotropium	$954	$1,735	$2,467	42%	37%		BI
37	45		Topamax	Topiramate	$1,601	$2,027	$2,453	21%	15%		J&J
38	23		Avandia	Rosiglitazone	$2,252	$3,043	$2,440	-20%	3%		GSK
39	46		Prevnar	vaccine	$1,373	$1,961	$2,439	24%	21%		Wyeth
40	48		Zetia	Ezetimibe	$1,196	$1,929	$2,400	24%	26%		Merck & Co., Schering-Plough
41	38		Eloxatin	Oxaliplatin	$1,957	$2,127	$2,330	10%	6%		Sanofi-Aventis
42	44		Celebrex	Celecoxib	$1,672	$2,039	$2,300	13%	11%		Pfizer
43	34		Zyrtec	Cetirizine	$2,163	$2,377	$2,277	-4%	2%		Pfizer, UCB, Daiichi Sankyo
44	51		Lamictal	Lamotrigine	$1,493	$1,843	$2,196	19%	14%		GSK
45	32		Aricept	Donepezil	$1,914	$2,519	$2,175	-14%	4%		Eisai, Pfizer
46	58		Micardis	Telmisartan	$1,069	$1,645	$2,125	29%	26%		BI, Astellas Pharma
47	75		Cymbalta	Duloxetine	$79	$1,316	$2,100	60%	198%		Eli Lilly
48	64		Levaquin	Levofloxacin	$1,545	$1,863	$2,047	10%	10%		J&J, Daiichi
49	14		Protonix	Pantoprazole	$3,476	$3,621	$1,987	-45%	-17%		Wyeth, Altana, Solvay
50	31		Ambien	Zolpidem	$1,705	$2,545	$1,910	-25%	4%		Sanofi-Aventis
51	66		Prograf	Tacrolimus	$1,199	$1,499	$1,876	25%	16%		Astellas Pharma
52	56		Avonex	Interferon beta-1a	$1,519	$1,707	$1,870	10%	7%		Biogen
53	63		Valtrex	Valaciclovir	$1,188	$1,563	$1,870	20%	16%		GSK
54	61		TriCor	Fenofibrate	$972	$1,567	$1,811	16%	23%		Abbott , Solvay
55	57		Viagra	Sildenafil	$1,640	$1,657	$1,764	6%	2%		Pfizer
56	53		Epogin	Erythropoietin	$1,795	$1,778	$1,750	-2%	-1%		Roche, Chugai
57	40		Tamiflu	Oseltamivir	$650	$2,096	$1,739	-17%	39%		Roche, Chugai
58	65		Arimidex	Anastrozole	$1,086	$1,508	$1,730	15%	17%		AstraZeneca
59	26		Copaxone	Glatiramer	$1,009	$1,414	$1,713	21%	19%		Teva Industries, Sanofi-Aventis
60	69		Rebif	Interferon beta-1a	$1,249	$1,452	$1,670	15%	10%		Serono
61	50		Abilify	Aripiprazole	$1,008	$1,282	$1,660	29%	18%		Otsuka , BMS
62	68		Xalatan	Latanoprost	$1,366	$1,453	$1,604	10%	6%		Pfizer
63	71		Gemzar	Gemcitabine	$1,338	$1,408	$1,590	13%	6%		Eli Lilly
64	88		Truvada	Tenofovir + Emtricitabine	$(119)	$1,194	$1,590	33%	-337%		Gilead Sciences
65	60		Lupron	Leuprolide	$1,563	$1,810	$1,582	-13%	0%		Takeda , TAP
66	77		Depakote	Valproate semisodium	$1,059	$1,308	$1,575	20%	14%		Abbott
67	89		Symbicort	Budesonide + Formoterol	$971	$1,184	$1,575	33%	18%		AstraZeneca
68	78		Humalog	Insulin analog	$1,196	$1,300	$1,470	13%	7%		Eli Lilly
69	80		Pulmicort	Budesonide	$1,150	$1,292	$1,454	13%	8%		AstraZeneca
70	52		Toprol	Metoprolol	$1,741	$1,795	$1,438	-20%	-6%		AstraZeneca
71	112		Cialis	Tadalafil	$680	$971	$1,430	47%	28%		Lilly, Lilly Icos
72	82		Betaseron	Interferon beta-1b	$1,071	$1,245	$1,409	13%	10%		Schering AG
73	92		Flomax	Tamsulosin	$834	$1,158	$1,380	19%	18%		BI
74	76		Imitrex	Sumatriptan	$1,262	$1,315	$1,371	4%	3%		GSK
75	90		Pegasys	Peg-interferon alfa-2a	$1,112	$1,171	$1,370	17%	7%		Roche, Chugai
76	73		Benicar	Olmesartan	$370	$1,370	$1,343	-2%	54%		Daiichi Sankyo, Forest
77	98		Erbitux	Cetuximab	$473	$1,075	$1,336	24%	41%		BMS, Merck KGaA
78	86		Casodex	Bicalutamide	$1,122	$1,206	$1,335	11%	6%		AstraZeneca
79	81		Zometa	Zoledronate	$1,219	$1,283	$1,300	1%	2%		Novartis
80	85		Neupogen	Filgrastim	$1,213	$1,213	$1,277	5%	2%		Amgen
81	84		Flovent	Fluticasone	$1,158	$1,219	$1,243	2%	2%		GSK
82	108		Botox	Botulin toxin	$805	$982	$1,211	23%	15%		Allergan